Summary
The changes induced by the deficiency of calories or nitrogen on the protein metabolism in rats were investigated. Animals were fed either a restricted normal diet, a protein-deficient diet or control dietad libitum. Rats receiving protein-free diet failed to grow, while the growth of animals given restricted diet was less than those fedad libitum. Despite that, the dietary deficiency of either calories or proteins caused the loss of protein and increased the incorporation of 1−C14 glycine into liver proteins. The contents of liver-free amino acids and urea were significantly increased only in the protein-deficient rats.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Anne, S., D. S. Robinson: The effect of the administration of carbon tetrachloride on the formation of plasma lipoprotein in the rat. Biochem. J.86, 401 (1963).
Ashwark, A., R. Bell, W. P. T. James, J. C. Waterlow; Lancet1968/II, 600. Cited from Advances proteins. Chemistry (New York-London 1971).
Beaton, J. R., V. Feleki, J. A. F. Stevens: Factors in the reduced food intake of rats fed a low protein diets. Can. J. Physical Pharmacol.46, 19 (1968).
Boas, Fixen, Jackson: The biological value of proteins of wheat, maize and milk. Biochem. J.26, 1923 (1932).
Brown, R. A., M. Sturtevent: Vitamines and Hormones7, 171 (1949).
Carwary, W. T.: Standard methods of clinical chemistry, ed.Seligson, D. Academic Press, New York and London4, 239 (1963). Cited from Practical Clinical Biochemistry,Harold Varely, 4th edition, p. 190. Interscience Book Inc. (New York 1969).
Dean, R. F. A.: Recent advances in Pediatrics, 3rd edition, ed.Gairdner Churchill Ltd. (1965).
Follis, R. H.: Progress in meeting protein needs of infants and preschool children, p. 377 Nat. Acad. Sci. National Research Council (Washington D.C. 1961).
Ganong, F. W.: Endocrinology and Metabolism.IV, 17, 218–255 (1969). Review of Medical Physiology — Edition IV. Long Medical Publication p. 244.
Hubbel, Mendel, Waksman: U. Nut.14, 373 (1937).
Jelliffe, D. B.: World Health Organization, Geneva (1966). Cited from Ph.D. Thesis ofSohir Salim, National Research Centre, 1968.
Lowery, O. H., N. G. Rosebrough, L. A. Farr, R. G. Randell: J. Biol. Chem.193, 265 (1951). Cited from Practical Clinical Biochemistry. Harold Varely, 4th Edition, p. 230 (New York 1969).
Luean, E. A., J. C. Edozien: Experimental protein and energy deficiencies in the rats. J. Nutr.105, 631 (1975).
Mayer, J. H., W. A. Hargus: Factors influencing food intake of rats fed low protein rations. Amer. J. Physiol.197, 1350 (1959).
Natelson, S.: Microtechniques of clinical chemistry for the routine, p. 381 (Springfield, Ill. 1957).
Peter, S. T., C. Jerry, S. Oram, J. L. Maria, W. W. Herbest, C. L. Linda, M. L. Johnne: Effect of nitrogen and calorie restriction on protein synthesis in the rat. Amer. J. Physiol.230, 1321 (1976).
Platt, B. S.: Progress in meeting protein needs of infants and preschool children, p. 383. Nat. Acad. Sci. National Research Council (Washington, D.C. 1961).
Strikland, R. D., M. L. Freeman, F. T. Gurule: Anal. Chem.33, 545. Cited from Practical clinical chemistry.Gelson, T., andPhilip, G. A. p. 171 (Boston 1975).
Waterlow, J. C., V. G. Wills: Balance studies in malnourished Jamaican infants. Brit. J. Nutr.14, 183 (1960).
Yen-Shan, P., L. M. Larry, G. V. Mitchell, R. K. Arthur: Changes in food intake and nitrogen; metabolism of rats while adapting a low or high protein diet. J. Nutr.104, 1008 (1974).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Moustafa, A.E.H.A., Borai, I.H. & Shoukry, S. Effect of calories restriction and protein deficiency on protein metabolism in rats. Z Ernährungswiss 19, 166–172 (1980). https://doi.org/10.1007/BF02018782
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02018782