Pediatric Radiology

, Volume 21, Issue 4, pp 247–249 | Cite as

Height of normal pituitary gland as a function of age evaluated by magnetic resonance imaging in children

  • M. Argyropoulou
  • F. Perignon
  • F. Brunelle
  • R. Brauner
  • R. Rappaport


MR anatomy of hypothalamo-hypophyseal axis is well established. However data about pituitary gland height (PGH) in children are sparse. A retrospective study was therefore performed in 60 children (30 boys and 30 girls) aged from 8 days to 21 years. All these children had MR for various neurological diseases. Patients with hypothalamo-hypophyseal disease and intracranial hypertension were excluded. The PGH was measured on a strict midline sagittal T1 weighted scan 3 to 7 mm thick. A positive linear correlation was found in children aged from 1 year to puberty followed by a plateau. In the first year of life a negative linear correlation was found. A positive linear correlation was found between PGH and statural height as well.


Public Health Hypertension Magnetic Resonance Imaging Retrospective Study Neurological Disease 
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  1. 1.
    Daniels LD, Pojunas WK, Kilgore PD et al. (1986) MR of the diaphragma sellae. AJNR 7: 765PubMedGoogle Scholar
  2. 2.
    Di Chiro G, Nelson KB (1962) The volume of the sella turcica. Am J Roentgenol 87: 989Google Scholar
  3. 3.
    Fujisawa I, Asato R, Nishimura K et al. (1987) Anterior and posterior lobes of the pituitary gland: assessment by 1.5 T MR imaging. J Comput Assist Tomogr 22: 314Google Scholar
  4. 4.
    Fujisawa I, Asata R, Kawata M et al. (1989) Hyperintense signal of the posterior pituitary on T1 weighted MR images: an experimental study. J Comput Assist Tomogr 13: 371PubMedGoogle Scholar
  5. 5.
    Gudinchet F, Brunelle F, Barth MO et al. (1989) MR imaging of the posterior hypophysis in children. AJNR 10: 511Google Scholar
  6. 6.
    Hayakawa K, Konishi Y, Matsuda T et al. (1989) Development and aging of brain midline structures: assessment with MR imaging. Radiology 172: 171PubMedGoogle Scholar
  7. 7.
    Inove Y, Nemoto Y, Fujita K et al. (1986) Pituitary dwarfism: CT evaluation of the pituitary gland. Radiology 159: 171PubMedGoogle Scholar
  8. 8.
    Kalifa G, Demange Ph, Sellier N et al. (1986) Magnetic resonance imaging (MRI) of the sellar and juxta sellar area in children. Ann Radiol 29: 669PubMedGoogle Scholar
  9. 9.
    Kaplan SL, Grumbach MM, Aubert ML (1976) The ontogenesis of pituitary hormones and hypothalamic factors in the human fetus. Maturation of central nervous system. Regulation of anterior pituitary function. Rec Progr Horm Res 32: 161PubMedGoogle Scholar
  10. 10.
    Wiener S, Rzeszotarski M, Droege R et al. (1985) Measurement of pituitary gland height with MR imaging. AJNR 6: 717PubMedGoogle Scholar
  11. 11.
    Wolpert S, Molitch M, Goldman J et al. (1984) Size, shape and appearance of the normal female pituitary gland. AJR 143: 377PubMedGoogle Scholar

Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • M. Argyropoulou
    • 1
  • F. Perignon
    • 2
  • F. Brunelle
    • 1
  • R. Brauner
    • 2
  • R. Rappaport
    • 2
  1. 1.Service de Radiologie PediatriqueHoptal des Enfants-MaladesParis Cedex 15France
  2. 2.Service d'Endocrinologie PédiatriqueHopital des Enfants-MaladesParis Cedex 15France

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