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Comparative in vitro activity of the new oral cephalosporin BMY-28100

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Abstract

Using a broth microdilution method, the in vitro activity of BMY-28100 against 365 clinical strains of commonly isolated bacteria was determined. BMY-28100 showed good activity against streptococci, methicillin-susceptible staphylococci,Salmonella spp.,Shigella spp., and beta-lactamase producing Branhamella catorrhalis and Haemophilus influenzae.Against susceptible strains of these organisms, BMY-28100 showed activity comparable to that of penicillin G, ampicillin, co-trimoxazole, erythromycin, cefaclor, doxycycline and amoxicillin/potassium clavulanate. BMY-28100 had moderate activity against Arizona hinshawii and poor activity against Campylobacter jejuni and Yersinia enterocolitica.

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Reference

  1. National Committee for Clinical Laboratory Standards: Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Approved standard M7-A. Villanova, PA, 1985.

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Authors and Affiliations

  1. Department of Medicine, Louisiana State University Medical Center, 1542 Tulane Avenue, 70112-2822, New Orleans, Louisiana, USA

    K. E. Aldridge, D. D. Schiro & C. V. Sanders

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  1. K. E. Aldridge
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  2. D. D. Schiro
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  3. C. V. Sanders
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Aldridge, K.E., Schiro, D.D. & Sanders, C.V. Comparative in vitro activity of the new oral cephalosporin BMY-28100. Eur. J, Clin. Microbiol. 6, 170–172 (1987). https://doi.org/10.1007/BF02018202

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  • DOI: https://doi.org/10.1007/BF02018202

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