European Journal of Clinical Microbiology

, Volume 6, Issue 3, pp 352–356 | Cite as

Clostridium difficile-Associated diarrhoea in uremic patients

  • B. Aronsson
  • P. Barany
  • C. E. Nord
  • B. Nyström
  • P. Stenvinkel
Article Current Topic: Control of Hospital-Acquired Infection


An outbreak of 94 episodes ofClostridiumdifficile-associated diarrhoea in 62 patients in a nephrology ward over a two-year period was investigated. Quantitative stool cultures were performed on ten uremic patients not on antibiotics and without diarrhoea and on ten healthy controls. All diarrhoeal episodes were associated withClostridium difficile,and no other bacterial pathogens were isolated. Thirty-two relapses occurred in 16 patients, fourteen of the relapses without preceding antibiotic exposure.Clostridium difficilecould not be isolated from the environment of the patients. Uremic patients, who had a significantly increased number ofClostridiumspp. in their stools, are predisposed toClostridium difficileinfections.


Internal Medicine Bacterial Pathogen Uremic Patient Stool Culture Antibiotic Exposure 
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Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1987

Authors and Affiliations

  • B. Aronsson
    • 1
  • P. Barany
    • 2
  • C. E. Nord
    • 3
  • B. Nyström
    • 3
  • P. Stenvinkel
    • 2
  1. 1.Department of Infectious DiseasesRoslagstull Hospital, Karolinska InstituteStockholmSweden
  2. 2.Department of NephrologyHuddinge University Hospital, Karolinska InstituteHuddingeSweden
  3. 3.Department of MicrobiologyHuddinge University Hospital, Karolinska InstituteHuddingeSweden

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