Abstract
Nosocomial infections withKlebsiella spp. are a leading cause of morbidity and mortality. The ability ofKlebsiella spp. readily to colonize hospitalized patients, complications in treatment of infections due to R-factor-acquired antibiotic resistance, and the high mortality rate in certain Patient populations, point to the need for immunoprophylactic/immunotherapeutic agents for disease control. The potential for vaccination againstKlebsiella spp. is discussed in light of recent developments concerning the pathogenesis ofKlebsiella infections as relates to the identification of protective antigens as possible vaccine candidates.
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Cryz, S.J. Progress in immunization againstKlebsiella infections. Eur. J, Clin. Microbiol. 2, 523–528 (1983). https://doi.org/10.1007/BF02016559
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DOI: https://doi.org/10.1007/BF02016559