Skip to main content
Log in

Barium enema findings in a case of Langerhans cell histiocytosis involving the colon

Pediatric Radiology Aims and scope Submit manuscript

Cite this article


Gastrointestinal (GI) tract involvement in Langerhans cell histiocytosis is probably not uncommon [1, 2], but reports of radiologic findings have been limited to the small intestine and mesenteric lymph nodes [3–5]. We report a 16-month-old child with known Langerhans cell histiocytosis, who was found to have mucosal irregularities of the colon as seen on air contrast barium enema, and was subsequently found to have diffuse involvement of the colon histologically confirmed by multiple biopsies.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others


  1. Boccon-Gibod LA et al (1992) Digestive tract involvement with exudative enteropathy in Langerhans cell histiocytosis. Pediatr Pathol 12:515–524

    PubMed  Google Scholar 

  2. Egeler RM, Schipper MEI, Heymans HSA (1990) Gastrointestinal involvement in Langerhans cell histiocytosis (histiocytosis X): a clinical report of three cases. Eur J Pediatr 149:325–329

    PubMed  Google Scholar 

  3. Feinberg SB, Lester RG (1958) Roentgen examination of the gastrointestinal tract as an aid in the diagnosis of acute and subacute reticuloendotheliosis. Radiology 71:525–532

    PubMed  Google Scholar 

  4. Parker BR, Castellino RA (1977) Lymphoreticular malignancies. In: Pediatric oncologic radiology. Mosby, St Louis, pp 230–231

    Google Scholar 

  5. Patel BJ, Chippindale AJ, Gupta SC (1991) Case report: small bowel histiocytosis-X. Clin Radiol 44:62–63

    PubMed  Google Scholar 

  6. Histiocyte Society Writing Group (1987) Histiocytosis syndromes in children. Lancet I:208–209

    Google Scholar 

  7. Hyams JS, Haswell JE, Gerber MA, Berman MM (1985) Colonic ulceration in histiocytosis X. J Pediatr Gastroenterol Nutr 4: 286–290

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations


Rights and permissions

Reprints and Permissions

About this article

Cite this article

Gilmore, B.S., Cohen, M. Barium enema findings in a case of Langerhans cell histiocytosis involving the colon. Pediatr Radiol 23, 589–590 (1993).

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: