Pathogenicity of piliated and encapsulatedBacteroides fragilis
Of 20 isolates of theBacteroides fragilis group, only three were encapsulated (C+) and these induced abscesses in mice. After coinoculation with live, formalized or capsular material from other bacteria seven other isolates formed abscesses. TheBacteroides recovered from these abscesses were C+; those that had been inoculated withKlebsiella had pili-like and bacteriophage-like structures. Once encapsulated, theBacteroides isolates induced abscesses when injected alone.
KeywordsInternal Medicine Capsular Material
Every, D., Skerman, T. M.
: Ultrastructure of theBacteroides nodosus
cell envelope layers and surface. Journal of Bacteriology 1980, 141: 845–857.PubMedGoogle Scholar
Brook, I., Coolbaugh, J. C., Walker, R. I.
: Antibiotic and clavulanic acid treatment of subcutaneous abscesses caused byBacteroides fragilis
alone or in combination with aerobic bacteria. Journal of Infectious Diseases 1983, 148: 156–158.PubMedGoogle Scholar
Onderdonk, A. B., Kasper, D. L., Cisneros, R. L., Bartlett, J. G.
: The capsular polysaccharide ofBacteroides fragilis
as a virulence factor: comparison of the pathogenic potential of encapsulated strains. Journal of Infectious Diseases 1977, 136: 82–89.PubMedGoogle Scholar
Brook, I., Gillmore, J. D., Coolbaugh, J. C., Walker, R. I.
: Pathogenicity of encapsulatedBacteroides melaninogenicus
, andBacteroides ruminicola
in abscesses in mice. Journal of Infection 1983, 7: 218–226.PubMedGoogle Scholar
Booth, S. J., Van Tasseli, R. L., Johnson, J. L., Wilkins, T. D.
: Bacteriophages ofBacteroides
. Reviews of Infectious Diseases 1979, 1: 325–334.PubMedGoogle Scholar
Onderdonk, A. B., Moon, N. F., Kasper, D. L., Bartlett, J. G.
: Adherence ofBacteroides fragilis
in vivo. Infection and Immunity 1978, 19: 1083–1087.PubMedGoogle Scholar