Abstract
Crude soluble antigens were evaluated with indirect haemagglutination and ELISA for their specificity in the immunodiagnosis of alveolar and cystic echinococcosis. Using a combination of heterologous crude antigens, the ELISA method made a correct species-specific diagnosis in 96.3 % of the patients. These results are similar to those obtained by immuno-diagnosis with purified antigens.
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Mannweiler, E., Thöle, A., Lederer, I.: Beiträge zur Immundiagnostik der Echinokokkose des Menschen. Zentralblatt für Bakteriologie und Hygiene 1977, 238: 494–502.
Knobloch, J., Lederer, I.: Immunodiagnosis of human paragonimiasis by an enzyme immunoassay. Tropenmedizin und Parasitologie 1983, 34: 21–23.
Schantz, P. M., Shanks, D., Wilson, M.: Serologic cross-reactions with sera from patients with echinococcosis and cysticercosis. American Journal of Tropical Medicine and Hygiene 1980, 29: 609–612.
Kagan, I. G., Norman, L., Allain, D. S.: Studies on echinococcosis: serology of crude and fractionated antigens prepared fromEchinococcus granulosus andEchinococcus multilocularis. American Journal of Tropical Medicine and Hygiene 1960, 9: 248–261.
Ballad, N. E., Lejkona, E. S., Jegorow, A. M., Gawrilowa, E. M., Sorichina, W. D.: Efficacy of different modifications of the enzyme immunoassay with purified antigens ofAlveococcus for the diagnosis of human alveococcosis (in Russian). Medicinskaja Parazitologija 1982, 51: 66–70.
Gottstein, B., Eckert, J., Fey, H.: Serological differentiation betweenEchinococcus granulosus andEchinococcus multilocularis infections in man. Zeitschrift für Parasitenkunde 1983, 69: 347–356.
Mannweiler, E., Felgner, P., Lederer, I.: Serum-Antikörper bei der zystischen und alveolären Echinokokkose. Deutsche Medizinische Wochenschrift 1979, 104: 1139–1142.
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Knobloch, J., Lederer, I. & Mannweiler, E. Species-specific immunodiagnosis of human echinococcosis with crude antigens. Eur. J, Clin. Microbiol. 3, 554–555 (1984). https://doi.org/10.1007/BF02013618
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DOI: https://doi.org/10.1007/BF02013618