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Evaluation of the Cobasbact system for rapid antimicrobial susceptibility testing of positive blood culture broths

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Abstract

The automated Cobasbact system was adapted for direct antimicrobial susceptibility testing of positive blood culture broths and its performance compared with that of the conventional Kirby-Bauer agar disc diffusion method using 278 positive blood samples. Overall, 1746 antibiotic-organism combinations were tested. Full agreement was 86.9 % and essential agreement (i.e. including minor discrepancies) was 91.8 %. The system would seem to produce acceptable susceptibility results within five hours after detection of a positive blood culture broth.

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  1. Laboratoire de Bactériologie Medicale, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

    W. Kamm & J. Bille

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  1. W. Kamm
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  2. J. Bille
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Kamm, W., Bille, J. Evaluation of the Cobasbact system for rapid antimicrobial susceptibility testing of positive blood culture broths. Eur. J, Clin. Microbiol. 4, 579–582 (1985). https://doi.org/10.1007/BF02013399

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  • DOI: https://doi.org/10.1007/BF02013399

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