Incorporation of tetracycline into impeded and unimpeded mandibular incisors of the mouse
- 24 Downloads
Twenty-four hours after a tetracycline injection, the unimpeded, and more rapidly erupting, mouse mandibular incisor contained 20% to 44% more tetracycline than the contralateral, uncut incisor. It was concluded that the increased tetracycline incorporation reflected a higher rate of mineralization associated with faster tooth formation in the unimpeded tooth.
By measuring the amount of tetracycline which became incorporated at different times after an incisor was shortened, it was possible to investigate an early stage of the response of the incisor to cutting. A significant increase in the capacity of the tooth to incorporate tetracycline was detectable 4 h after shortening the tooth, and this was maximal after another 4 h.
Key wordsTetracycline Incisor growth Incisor unimpeded eruption
Unable to display preview. Download preview PDF.
- 3.Kohn, K.W.: Determination of tetracycline by extraction of fluorescent complexes. Anal. Chem.33, 862–866 (1961)Google Scholar
- 6.Steendijk, R.: Studies on the mechanism of the fixation of the tetracycline to bone. Acta Anat. (Basel)56, 368–382 (1964)Google Scholar
- 9.Schour, I., Medak, H.: Experimental increase in rate of eruption and growth of rat incisor by eliminating attrition. J. Dent. Res.30, 521 (Abst.) (1951)Google Scholar
- 10.Robins, M.W.: Growth and eruption of the rat incisor. Ph.D. Thesis, University of London, London (1968)Google Scholar