, Volume 41, Issue 6, pp 762–764 | Cite as

Microbial methylation of benzenethiols and release of methylthiobenzenes

  • A. -M. Drotar
  • R. Fall
Short Communications Ethology, Ecology, Natural Product Chemistry


Three phylogenetically diverse microorganisms methylated several different chloro- and nitro-substituted benzenethiols to yield the corresponding methylthiobenzenes. These products were identified by gas chromatography-mass spectrometry. In several cases large percentages of the methylthio products were released by intact cells into the medium, suggesting that microbial methylation of xenobiotic thiols may be a significant biotransformation in many ecosystems.

Key words

Methylthiobenzenes benzenethiols xenobiotics ecosystems 


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  1. 3.
    Tateishi, M., Suzuki, S., and Shimizu, H., J. biol. Chem.253 (1978) 8854.PubMedGoogle Scholar
  2. 4.
    Bakke, J. E., and Price, C. E., J. envir. Sci. HealthB 14 (1979) 427.Google Scholar
  3. 5.
    Begum, S., Scheunert, I., Haque, A., Klein, W., and Korte, F., Pesticide Biochem. Physiol.11 (1979) 189.Google Scholar
  4. 6.
    Koss, G., Koransky, W., and Steinbach, K., Archs Toxic.42 (1979) 19.Google Scholar
  5. 7.
    Stillwell, W. G., Bouwsma, O. J., Thenot, J.-P., Horning, M. G., Griffin, G. W., Ishikawa, K., and Takaku, M., Res. Commun. Chem. Path. Pharmac.20 (1979) 509.Google Scholar
  6. 8.
    Lamoureux, G. L., and Rusness, D. G., ACS Symp. Ser.158 (1981) 133.Google Scholar
  7. 9.
    Renner, G., Xenobiotica11 (1981) 435.PubMedGoogle Scholar
  8. 10.
    Lau, E. P., Niswander, L., Watson, D., and Fall, R. R., Chemosphere9 (1980) 565.Google Scholar
  9. 11.
    Murphy, S. E., Drotar, A. M., and Fall, R., Chemosphere11 (1982) 33.Google Scholar
  10. 12.
    Drotar, A. M., Ph. D. Thesis, University of Colorado, 1982.Google Scholar
  11. 13.
    Ogrydziak, D., Bassel, J., Contopoulou, R., and Mortimer, R., Molec. gen. Genet.163 (1978) 229.Google Scholar
  12. 14.
    Weisiger, R. A., Pinkus, L. M., and Jakoby, W. B., Biochem. Pharmac.29 (1980) 2885.Google Scholar
  13. 15.
    Alexander, M., Science211 (1981) 132.PubMedGoogle Scholar
  14. 16.
    Bergman, A., Brandt, I., Darnerud, P. O., and Wachmeister, C. A., Xenobiotica12 (1982) 1.PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag Basel 1985

Authors and Affiliations

  • A. -M. Drotar
    • 1
  • R. Fall
    • 1
  1. 1.Department of Chemistry, and Cooperative Institute for Research in Environmental SciencesUniversity of ColoradoBoulderUSA

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