Experientia

, Volume 41, Issue 6, pp 743–745 | Cite as

Calcium transport by red blood cell membranes from young and adult cattle

  • A. Zimmermann
  • H. J. Schatzmann
Short Communications Cellular and Molecular Biology, Immunology
  • 12 Downloads

Summary

It is shown using inside-out membrane vesicles that cattle red cells extrude calcium by means of a calmodulin sensitive Ca-pump whose activity is high in calves and extremely low in adult cows. The deline is not due to loss of calmodulin susceptibility nor to a drop in Ca-affinity.

Key words

Red blood cells bovine calcium transport membrane vesicles calmodulin calcium concentration intracellular 

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References

  1. 1.
    Brown, A. M., Ellory, J. C., Young, J. D., and Lew, V. L., Biochim. biophys. Acta511 (1978) 163.PubMedGoogle Scholar
  2. 2.
    Christinaz, P., and Schatzmann, H. J., J. Physiol.224 (1972) 391.PubMedGoogle Scholar
  3. 3.
    Schatzmann, H. J., Nature248 (1974) 58.PubMedGoogle Scholar
  4. 4.
    Ellory, J. C., and Tucker, E. M., J. Physiol.204 (1969) 101P.Google Scholar
  5. 5.
    Israel, Y., Macdonald, A., Bernstein, J., and Rosenmann, E., J. gen. Physiol.59 (1972) 270.PubMedGoogle Scholar
  6. 6.
    Tucker, E. M., Smalley, C. E., Ellory, J. C., and Dunham, P. B., J. gen. Physiol.79 (1982) 893.PubMedGoogle Scholar
  7. 7.
    Schatzmann, H. J., and Scheidegger, H. R., Experientia31 (1975) 1260.PubMedGoogle Scholar
  8. 8.
    Steck, T. L., Weinstein, R. S., Straus, J. H., and Wallach, D. F. H., Science168 (1970) 255.PubMedGoogle Scholar
  9. 9.
    Wüthrich, A., and Schatzmann, H. J., Cell Calcium1 (1980) 21.Google Scholar
  10. 10.
    Schatzmann, H. J., J. Membr. Biol.35 (1977) 149.PubMedGoogle Scholar
  11. 11.
    Gietzen, K., Wüthrich, A., and Bader, H., Molec. Pharmac.22 (1982) 413.Google Scholar
  12. 12.
    Martonosi, A. N., in: Muscle and Nonmuscle Motility, vol. 1, p. 233. Academic Press, New York and London 1983.Google Scholar
  13. 13.
    Gietzen, K., Adamczyk-Engelmann, P., Wüthrich, A., Konstantinova, A., and Bader, H., Biochim. biophys. Acta736 (1983) 109.PubMedGoogle Scholar
  14. 14.
    Steck, T. L., and Kant, J. A., Meth. Enzym.31 (1974) 172.PubMedGoogle Scholar
  15. 15.
    Lowry, D. H., Rosebrough, J. N., Farr, A. L., and Randall, R. J., J. biol. Chem.193 (1951) 265.PubMedGoogle Scholar
  16. 16.
    Sillen, L. G., and Martell, A. E., Stability constants of metal ion complexes, 2nd edn, Special Publication No. 17. The Chemical Society, Burlington House, London 1964.Google Scholar

Copyright information

© Birkhäuser Verlag Basel 1985

Authors and Affiliations

  • A. Zimmermann
    • 1
  • H. J. Schatzmann
    • 1
  1. 1.Department of Veterinary PharmacologyUniversity of BernBernSwitzerland

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