Pediatric Radiology

, Volume 24, Issue 5, pp 316–318 | Cite as

Gorham's disease or vanishing bone disease: Plain film, CT, and MRI findings of two cases

  • R. Dominguez
  • T. L. Washowich


Gorham's disease may develop in any region of the skeleton, but shows a predilection for the bones of the shoulders and pelvic girdles. Less frequently, the disease may involve the spine, and it is the proximity to the spinal cord which may worsen the patient's outcome. We report the clinical outcomes of two children with typical, yet differently localized involvement, and also review the plain film, CT and MRI findings


Public Health Spinal Cord Clinical Outcome Bone Disease Plain Film 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Gorham L, Stout A (1955) Massive osteolysis (acute spontaneous absorption of bone, phantom bone, disappearing bone): its relation to hemangiomatosis. J Bone Joint Surg [Am] 37: 985–1004Google Scholar
  2. 2.
    Abrahams J, Ganick D, Gilbert E, Wolfson J (1980) Massive osteolysis in an infant. AJR 135: 1084–1086PubMedGoogle Scholar
  3. 3.
    Torg JS, DiGeorge AM, Kirkpatrick JA Jr, Trujillo MM (1969) Hereditary multicentric osteolysis with recessive transmission: a new syndrome. J Pediatr 75: 243–252PubMedGoogle Scholar
  4. 4.
    MacPherson RL, Walker RD, Kowall MH (1973) Essential osteolysis with nephropathy. J Can Assoc Radiol 24: 98–103PubMedGoogle Scholar
  5. 5.
    Patrick JH (1984) Massive osteolysis complicated by chylothorax successfully treated by pleurodesis. J Bone Joint Surg [Br] 66: 148–149Google Scholar
  6. 6.
    Hardegger F, Simpson LA, Segmueller G (1985) The syndrome of idiopathic osteolysis. J Bone Joint Surg [Br] 67: 89–93Google Scholar
  7. 7.
    Heyden G, Kindblom LG, Nielsen JM (1977) Disappearing bone disease. A clinical and histological study. J Bone Joint Surg [Am] 59: 57–61Google Scholar
  8. 8.
    Johnson P, McClure J (1958) Observations on massive osteolysis. Radiology 71: 28–41PubMedGoogle Scholar
  9. 9.
    Sage MR, Allen PW (1974) Massive osteolysis: report of a case. J Bone Joint [Br] 56: 130–134Google Scholar
  10. 10.
    Hejgaard N, Olsen PR (1987) Massive Gorham osteolysis of the right hemipelvis complicated by chylothorax: report of a case in a 9-year-old boy successfully treated by pleurodesis. J Pediatr Orthop 7: 96–99PubMedGoogle Scholar
  11. 11.
    Bullough P (1971) Massive osteolysis. N Y State J Med 71: 2267–2278PubMedGoogle Scholar
  12. 12.
    Siegel MJ, Glazer HS, St Amout TE, Rosenthal DD (1989) Lymphangiomas in children: MR imaging. Radiology 170: 467–570PubMedGoogle Scholar
  13. 13.
    Bullough P (1971) Massive osteolysis. NY State J Med 71: 2267–2278Google Scholar
  14. 14.
    King DJ (1946) A case, resembling hemangiomatosis of the lower extremity. J Bone Joint Surg 28: 623–628Google Scholar
  15. 15.
    Joseph J, Bartal E (1987) Disappearing bone disease: a case report and review of the literature. J Pediatr Orthop 7: 584–588PubMedGoogle Scholar

Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • R. Dominguez
    • 1
  • T. L. Washowich
    • 1
  1. 1.Department of RadiologyUniversity of Texas, Southwestern Medical Center and Children's Medical Center of DallasDallasUSA

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