Advertisement

Pediatric Radiology

, Volume 23, Issue 4, pp 253–257 | Cite as

Cervical neuroblastoma in eleven infants —a tumor with favorable prognosis

Clinical and radiologic (US, CT, MRI) findings
  • S. J. Abramson
  • W. E. Berdon
  • C. Ruzal-Shapiro
  • C. Stolar
  • J. Garvin
Article

Abstract

Cervical neuroblastoma, a disease primarily of infants, has a favorable prognosis. Eleven patients are reported. Clinical presentations (other than mass) included stridor and swallowing problems. Masses when felt were commonly mistaken for infectious adenitis. Imaging studies (US, CT, MRI) showed solid masses with vascular displacement and narrowing; intraspinal extension was absent though extension into the adjacent sites of mediastinum and skull occurred. Horner syndrome was seen in five patients with accompanying heterochromia iridis in one. Five tumors had calcification. A high index of suspicion will lead to biopsy and less delay in diagnosis once a mass is felt or imaged.

Keywords

Public Health Image Study Neuroblastoma High Index Favorable Prognosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Al Jassim AHH (1987) Cervical ganglioneuroblastoma. J Laryngol Otol 101: 296–301PubMedGoogle Scholar
  2. 2.
    Smith MCF, Smith RJH, Bailey CM (1985) Primary cervical neuroblastoma in infants. J Laryngol Otol 99: 209–214PubMedGoogle Scholar
  3. 3.
    Orr JD (1978) Cervical neuroblastoma in childhood — a better prognosis? Clin Oncol 4: 353–358PubMedGoogle Scholar
  4. 4.
    Baker ME, Kirks DR, Korobkin M, Bowie JD, Filston HC (1985) The association of neuroblastoma and myoclonic encephalopathy: an imaging approach. Pediatr Radiol 15: 185–189Google Scholar
  5. 5.
    Cushing BA, Slovis TL, Philippart AI, Lakshmi D, Watts FB Jr, Corbett DP, Reed JO, Hertzler HJ, Belenky W (1982) A rational approach to cervical neuroblastoma. Cancer 50: 785–787PubMedGoogle Scholar
  6. 6.
    Riggs W Jr, Benton C, Wood B (1977) Cervical neurogenic tumors presenting as thoracic apical masses in infants and children. Pediatr Radiol 5: 201CrossRefPubMedGoogle Scholar
  7. 7.
    Jaffe N, Cassady R, Filler RM, Peterson R, Traggis D (1975) Heterochromia and Horner syndrome associated with cervical and mediastinal neuroblastoma. J Pediatr 87: 75–77PubMedGoogle Scholar
  8. 8.
    McRae D, Shaw A (1979) Ganglioneuroma, heterchromia iridis, and Horner's syndrome. J Pediatr Surg 14: 612–614PubMedGoogle Scholar
  9. 9.
    Collin PP, Schmidt M, Bensoussan A, Blanchard H, Desjardins JG (1979) Neurogenic tumors and VIP-induced diarrhea. J Pediatr Surg 14: 525–526PubMedGoogle Scholar
  10. 10.
    Ogita S, Tokiwa K, Takahashi T, Imashuku S, Sawada T (1988) Congenital cervical neuroblastoma associated with Horner syndrome. J Pediatr Surg 23: 991–992PubMedGoogle Scholar
  11. 11.
    Gibb J, Appleton RE, Martin J, Findlay G (1992) Congenital Horner syndrome associated with non-cervical neuroblastoma. Dev Med Child Neurol 34: 642–644PubMedGoogle Scholar
  12. 12.
    Musarella M, Chan H, DeBoer G, Gallie G (1984) Ocular involvement in neuroblastoma: prognostic implications. Ophthalmology 91: 936–940PubMedGoogle Scholar
  13. 13.
    Plantaz D, Hartmann O, Kalifa C, Sainte-Rose C, Passagia JG, Lemerle J (1991) Neuroblastomes en sablier. Arch Fr Pediatr 48: 529–533PubMedGoogle Scholar
  14. 14.
    Carlsen NLT, Schroeder H, Bro PV, Erichsen G, Hamborg-Pedersen B, Bjoern Jensen K, Nielsen OH (1985) Neuroblastomas treated at the four major child oncologic clinics in Denmark 1943–1980: an evaluation of 180 cases. Med Pediatr Oncol 13: 180–186PubMedGoogle Scholar
  15. 15.
    Matthay KK, Sather HN, Seeger RC, Haase GM, Hammond GD (1989) Excellent outcome of stage II neuroblastoma is independent of residual disease and radiation therapy. J Clin Oncol 7: 236–244PubMedGoogle Scholar
  16. 16.
    Casselman JW, Smet MH, Van Damme B, Lemahieu SF (1988) Primary cervical neuroblastoma: CT and MR findings. JCAT 12: 684–686Google Scholar

Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • S. J. Abramson
    • 1
  • W. E. Berdon
    • 1
  • C. Ruzal-Shapiro
    • 1
  • C. Stolar
    • 2
  • J. Garvin
    • 3
  1. 1.Department of Pediatric Radiology, The Babies HospitalColumbia-Presbyterian Medical CenterUSA
  2. 2.Department of Pediatric Surgery, The Babies HospitalColumbia-Presbyterian Medical CenterNew YorkUSA
  3. 3.Department of Pediatric Hematology/Oncology, The Babies HospitalColumbia-Presbyterian Medical CenterNew YorkUSA

Personalised recommendations