Summary
1,25-dihydroxycholecalciferol (1,25-(OH)2D3), added at doses which stimulate bone resorption in the system used, did not increase adenosine 3′,5′-cyclic monophosphate (cAMP) production in vitro in mouse calvaria incubated for up to 48 h. Thus 1,25-(OH)2D3 does not appear to stimulate bone resorption through involvement of an increased cAMP production.
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Gebauer, U., Fleisch, H. Effect of 1,25-dihydroxycholecalciferol on adenosine 3′,5′-cyclic monophosphate production in calvaria of mice. Calc. Tis Res. 25, 223–225 (1978). https://doi.org/10.1007/BF02010773
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DOI: https://doi.org/10.1007/BF02010773