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Pediatric Radiology

, Volume 20, Issue 1–2, pp 61–66 | Cite as

Evaluation of potential practical oral contrast agents for pediatric magnetic resonance imaging

Preliminary observations
  • G. S. BissetIII
Originals

Abstract

Development of a practical oral contrast agent for magnetic resonance imaging is necessary to improve differentiation of bowel from adjacent structures. In order to find a readily available, inexpensive, non-toxic, palatable solution for use in the pediatric population, several formulas, milk products and a common oral sedative were evaluated in vitro. T1, T2 and signal intensity measurements were performed on a 1.5 T system. Similac with standard iron proved to be a useful high signal intensity agent on multiple pulse sequences. Early in vivo experience in four normal volunteers indicates that this agent provides excellent delineation of the stomach and duodenum from contiguous viscera. Distal small bowel visualization is less predictable. Further clinical trials should confirm the utility of this solution, which contains a combination of iron salts and paramagnetic metallic ions.

Keywords

Magnetic Resonance Imaging Small Bowel Milk Product High Signal Intensity Normal Volunteer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1989

Authors and Affiliations

  • G. S. BissetIII
    • 1
    • 2
  1. 1.Department of Radiology and PediatricsUniversity of Cincinnati College of MedicineCincinnatiUSA
  2. 2.Department of RadiologyChildren's Hospital Medical CenterCincinnatiUSA

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