Abstract
Using Anti Mouse Lymphocytic Serum as an immunosuppressor instead of steroid hormones, bone induction was obtained in mice grafted with K xenogenic-established epithelial cell line. The results suggest that bone induction in this experimental system is not dependent upon steroid hormones.
Résumé
En utilisant du sérum antilymphocytaire de souris, utilisé comme immuno-dépresseur à la place d'hormones stéroides, une induction de tissu osseux est obtenue chez la souris chez laquelle des cellules épithéliales souches K xénogéniques sont greffées. L'induction osseuse dans ce système expérimental n'est donc pas liée aux hormones stéroides.
Zusammenfassung
Mit dem als Immunosuppressor wirkenden Anti-Mäuse-Lymphocyten-Serum, welches anstelle von Steroidhormonen verwendet wurde, konnte bei Mäusen, die ein Transplantat von K-xenogenen, festgesetzten Epithelzellen erhalten hatten, das Einsetzen von Knochenwachstum hervorgerufen werden. Diese Resultate zeigen, daß in diesem Modell das Einsetzen des Knochenwachstums nicht von Steroidhormonen abhängig ist.
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Wŀodarski, K., Hancox, N.M. Antilymphocytic serum as immunosuppressant in experimental bone induction by xenogenic epithelial cells. Calc. Tis Res. 8, 262–264 (1971). https://doi.org/10.1007/BF02010145
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DOI: https://doi.org/10.1007/BF02010145