Abstract
Human epithelial tissue culture line cells (“K” line) were injected into the leg or abdominal wall muscle, or subcutaneously, in cortisone-conditioned rats. Cartilage and/or bone was induced readily in either of the muscular sites, but not subcutaneously.
Résumé
Des cellules épithéliales humaines, obtenues par culture de tissu (de lignée “K”), sont njectées dans les muscles de la cuisse et de la paroi abdominale ou dans le tissu sous-cutané de rats conditionnés par la cortisone. Du cartilage et/ou de l'os se forment dans le tissu musculaire, mais non dans le tissu sous-cutané.
Zusammenfassung
Zellen aus der Kultur von menschlichem Epithelialgewebe („K”-Stamm) wurden Cortisonvorbehandelten Ratten in die Bein- oder Bauchwandmuskulatur oder subcutan injiziert. Die Bildung von Knorpel und/oder Knochen wurde in diesen zwei Muskelgeweben leicht ausgelöst; dies war jedoch an den subcutan behandelten Stellen nicht der Fall.
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Hancox, N.M., Wŀodarski, K. The role of host site in bone induction by transplanted xenogenic epithelial cells. Calc. Tis Res. 8, 258–261 (1971). https://doi.org/10.1007/BF02010144
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DOI: https://doi.org/10.1007/BF02010144