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, Volume 41, Supplement 1, pp C49–C50 | Cite as

Immunohistochemical studies with skin mast cells

  • B. Schmolke
  • U. Amon
  • N. Zemcke
  • H. H. Wolff
Histamine Release and Mast Cells


Using different histochemical and immunohistochemical methods we demonstrate that isolated skin mast cells used for different pharmacological and biochemical studies exhibit the same staining pattern compared to skin mast cellsin situ. Surface structures and enzyme content of the cells appear not to be influenced by the isolation technique. We also observed no differences in the staining pattern of mast cells in neurofibroma, a cutaneous disorder characterized by an increase of mast cell numbers.


Mast Cell Surface Structure Immunohistochemical Study Staining Pattern Biochemical Study 
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Copyright information

© Birkhäuser Verlag 1994

Authors and Affiliations

  • B. Schmolke
    • 1
  • U. Amon
    • 1
  • N. Zemcke
    • 1
  • H. H. Wolff
    • 1
  1. 1.Department of DermatologyMedical University of LübeckLübeckGermany

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