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Experientia

, Volume 41, Issue 5, pp 634–636 | Cite as

Normetanephrine and metanephrine oxidized by both types of monoamine oxidase

  • O. Suzuki
  • T. Matsumoto
Short Communications Biochemistry and Biophysics, Metabolism, Neurobiology, Pharmacology

Summary

Both normetanephrine and metanephrine were found to be oxidized by both types of monoamine oxidase in mouse liver mitochondria. Both Km and Vmax values of type B MAO for both substrates were higher than those of type A MAO, which caused the shift of inhibition curves with clorgyline and deprenyl according to the increase in substrate concentration.

Key words

Mouse liver mitochondria normetanephrine metanephrine monoamine oxidase 

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Copyright information

© Birkhäuser Verlag 1985

Authors and Affiliations

  • O. Suzuki
    • 1
    • 2
  • T. Matsumoto
    • 1
    • 2
  1. 1.Department of Legal MedicineHamamatsu University School of MedicineHamamatsu(Japan)
  2. 2.Division of Oncology, First Department of SurgeryNagoya University School of MedicineNagoya(Japan)

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