Skip to main content

Circling behavior induced by phencyclidine in mice and its inhibition by naloxone

Experientia volume 41, pages 73–74 (1985)Cite this article

Summary

Phencyclidine (PCP), when given to mice, induces general hyperactivity and rapid circling, similar to that caused by morphine. These effects are partially antagonized by naloxone.

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

43,34 €

Price includes VAT (Finland)
Tax calculation will be finalised during checkout.

Literatur

  1. Glick, S. D., Simmerberg, G., and Greenstein, S., Brain Res.105 (1976) 363.

    Google Scholar 

  2. Keren, O., and Korczyn, A. D., Experientia34 (1978) 616.

    PubMed  Google Scholar 

  3. Glick, S. D., Cox, R. D., Jerussi, T. P., and Greenstein, S., J. Pharm. Pharmac.29 (1977) 51.

    Google Scholar 

  4. Korczyn, A. D., and Eshel, Y., Neuroscience4 (1979) 1085.

    PubMed  Google Scholar 

  5. Kanner, M. I., Finnegan, K. T., and Meltzer, H. Y., Psychopharmac. Commun.114 (1975) 393.

    Google Scholar 

  6. Finnegan, K. T., Kanner, M. I., and Meltzer, H. Y., Pharmac. biochem. Behav.5 (1976) 651.

    Google Scholar 

  7. Meltzer, H. Y., Sturgeon, R. D., Simonovic, M., and Fessler, R. G., Psychopharmac. Bull.16 (1980) 62.

    Google Scholar 

  8. Glick, S. D., Meibach, R. C., Cox, R. D., and Maayani, S., Brain Res.196 (1980) 99.

    PubMed  Google Scholar 

  9. Sturgeon, R. D., Fessler, R. G., London, S. F., and Meltzer, H. Y., Eur. J. Pharmac.76 (1981) 37.

    Google Scholar 

  10. Rabinowitz, R., Shlesinger, N., and Korczyn, A. D., Pharmac. Res. Commun.15 (1983) 963.

    Google Scholar 

  11. Murray, T. F., and Horita, A., Life Sci.24 (1979) 2217.

    PubMed  Google Scholar 

  12. Itzhak, Y., Kalir, A., Weissman, B., and Cohen, S., Eur. J. Pharmac.72 (1981) 305.

    Google Scholar 

  13. Eshel, Y., Sarne, Y., and Korczyn, A. D., Life Sci.32 (1981) 1053.

    Google Scholar 

  14. Itzhak, Y., Kalir, A., and Sarne, Y., Eur. J. Pharmac.73 (1981) 229.

    Google Scholar 

Download references

Author information

Affiliations

  1. Department of Physiology and Pharmacology, Sackler School of Medicine, Tel Aviv University, Ramat Aviv, 69978, Tel Aviv, Israel

    Y. Eshel & A. M. Korczyn

Authors
  1. Y. Eshel
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. M. Korczyn
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Acknowledgment. We are grateful to Professor A. Kalir for the donation of PCP. Correspondence and reprint requests should be addressed to A. M. Korczyn.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Eshel, Y., Korczyn, A.M. Circling behavior induced by phencyclidine in mice and its inhibition by naloxone. Experientia 41, 73–74 (1985). https://doi.org/10.1007/BF02005882

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02005882

Key words

  • Mice
  • circling behavior
  • phencyclidine
  • naloxone
  • hyperactivity