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H2 receptor antagonists and human granulopoiesis

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Summary

The effect of 2 H2 receptor antagonists (ranitidine and cimetidine) on the in vitro growth of human granulomonopoietic precursors (CFU-GM) was studied. Ranitidine, although having an anti H2 receptor activity much greater than that of cimetidine, displays the same toxicity for CFU-GM.

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Authors and Affiliations

  1. Clinica Medica A, Via Genova 3, I-10126, Torino, Italy

    M. Aglietta, A. Stacchini, F. Sanavio & W. Piacibello

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  1. M. Aglietta
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  2. A. Stacchini
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  3. F. Sanavio
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  4. W. Piacibello
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Additional information

Acknowledgments. This work was supported by CNR, Rome, PFCCN and AIRC, Milan.

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Aglietta, M., Stacchini, A., Sanavio, F. et al. H2 receptor antagonists and human granulopoiesis. Experientia 41, 375–376 (1985). https://doi.org/10.1007/BF02004513

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  • DOI: https://doi.org/10.1007/BF02004513

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