, Volume 32, Issue 7, pp 849–850 | Cite as

Effect of cholesterol oxidation on (Na+, K+) ATPase activity of erythrocyte membranes

  • D. Seiler
  • W. Fiehn
Specialia Chimica, Biochimica


By incubation of human erythrocyte ghosts with cholesterol oxidase (EC part of the cholesterol of the membrane is replaced by 4-cholesten-3-one. This alteration in the sterol composition is accompanied by an inhibition of the (Na+, K+) ATPase of the erythrocyte membrane.


Oxidation Cholesterol Ghost ATPase Activity Erythrocyte Membrane 
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Copyright information

© Birkhäuser Verlag 1976

Authors and Affiliations

  • D. Seiler
    • 1
  • W. Fiehn
    • 1
  1. 1.Medizinische Poliklinik der Universität HeidelbergHeidelberg(German Federal Republic, BRD)

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