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Experientia

, Volume 32, Issue 7, pp 849–850 | Cite as

Effect of cholesterol oxidation on (Na+, K+) ATPase activity of erythrocyte membranes

  • D. Seiler
  • W. Fiehn
Specialia Chimica, Biochimica

Summary

By incubation of human erythrocyte ghosts with cholesterol oxidase (EC 1.1.3.6) part of the cholesterol of the membrane is replaced by 4-cholesten-3-one. This alteration in the sterol composition is accompanied by an inhibition of the (Na+, K+) ATPase of the erythrocyte membrane.

Keywords

Oxidation Cholesterol Ghost ATPase Activity Erythrocyte Membrane 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Birkhäuser Verlag 1976

Authors and Affiliations

  • D. Seiler
    • 1
  • W. Fiehn
    • 1
  1. 1.Medizinische Poliklinik der Universität HeidelbergHeidelberg(German Federal Republic, BRD)

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