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Degradation of encephalitogenic protein in aerobic ascorbic acid solutions

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  • Chimica, Biochimica
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Summary

Aerobic ascorbic acid solutions are capable of extensively cleaving the peptide chain of the myelin basic protein. Cleavage occurred most readily with C-terminal to aspartic acid, serine, threonine, glutamic acid and leucine residues.

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Author information

Author notes

  1. A. B. Robinson

    Present address: Linus Pauling Institute of Science and Medicine, 94025, Menlo Park, California, USA

Authors and Affiliations

  1. The Salk Institute for Biological Studies, P.O. Box 1809, 92112, San Diego, California, USA

    F. C. Westall, M. Thompson & A. B. Robinson

  2. Linus Pauling Institute of Science and Medicine, 94025, Menlo Park, California, USA

    F. C. Westall, M. Thompson & A. B. Robinson

Authors
  1. F. C. Westall
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  2. M. Thompson
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  3. A. B. Robinson
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Additional information

This research was supported in part by the National Multiple Sclerosis Society, grant number RG928-A-1.

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Westall, F.C., Thompson, M. & Robinson, A.B. Degradation of encephalitogenic protein in aerobic ascorbic acid solutions. Experientia 32, 848–849 (1976). https://doi.org/10.1007/BF02003722

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  • DOI: https://doi.org/10.1007/BF02003722

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