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Effects of long-term feeding of glibenclamide on normal rats

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Summary

Prolonged administration of glibenclamide decreased blood sugar, liver glycogen and protein and increased liver and serum lipids and organic phosphates of liver in normal rats. A significant weight increase observed in glibenclamide group of rats is attributed to lipid accumulation.

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George, A.V., Augusti, K.T. Effects of long-term feeding of glibenclamide on normal rats. Experientia 32, 846–847 (1976). https://doi.org/10.1007/BF02003721

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