Abstract
Abstract
The diaper environment increases the coefficient of skin friction and compromises the function of the stratum corneum. In this study, the tribological and mycological benefit of the use of a miconazole nitrate-containing paste on diapered skin was evaluated. A total of 135 instrumental measurements of both erythema and stratum corneum alterations were made on alternate days for 3 weeks in 15 infants. Biometrological parameters were the chromacity a* of the skin and the squamometry index. Cultures testing forCandida albicans were also performed. In the days following the use of the paste, the chromacity a*, the squamometry index and the number of positive cultures ofC. albicans were significantly reduced compared to the same evaluations made off treatment.
Conclusion
Miconazole nitratecontaining paste reduces the tribological interference between cloth diapers and skin as well as providing the diapered skin with an improved microbial environment.
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Piérard-Franchimont, C., Letawe, C. & Piérard, G.E. Tribological and mycological consequences of the use of a miconazole nitrate-containing paste for the prevention of diaper dermatitis: an open pilot study. Eur J Pediatr 155, 756–758 (1996). https://doi.org/10.1007/BF02002901
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DOI: https://doi.org/10.1007/BF02002901