, Volume 33, Issue 3, pp 382–383 | Cite as

3-Amino-1-(3,4-dichloro-α-methyl-benzyl)-2-pyrazolin-5-one (Bay g 2821), a potent diuretic from a new substance class

  • E. Möller
  • H. Horstmann
  • K. Meng
  • D. Loew


Chemistry, salidiuretic activity and mechanism of action of 3-amino-1-(3,4-dichloro-α-methyl-benzyl)-2-pyrazolin-5-one (Bay g 2821), a new diuretic, are described. Owing to the initial rapid onset of activity, the reserve in capacity and the additional long duration of activity, this substance represents a potent diuretic and antihypertensive agent.


Antihypertensive Agent Rapid Onset Substance Class Potent Diuretic Initial Rapid Onset 
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Copyright information

© Birkhäuser Verlag 1977

Authors and Affiliations

  • E. Möller
    • 1
  • H. Horstmann
    • 1
  • K. Meng
    • 1
  • D. Loew
    • 1
  1. 1.Pharma-ForschungszentrumBayer AGWupperta(BRD)

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