, Volume 33, Issue 3, pp 311–312 | Cite as

Effects of ethidium bromide in diploid and duplication strains of Aspergillus nidulans

  • R. BonatelliJr
  • J. L. Azevedo


Unstable duplication and diploid strains of Aspergillus nidulans were treated with ethidium bromide, and it was shown that this drug reduces the number of sectors produced by such strains. The mechanisms which could be responsible for the partial stabilization of the strains are discussed and it is suggested that a similar mechanism is responsible for the production of sectors in both strains. It is also suggested that ethidium bromide could be useful for the reduction of instability of industrial strains.


Bromide Aspergillus Ethidium Ethidium Bromide Aspergillus Nidulans 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 2.
    B. W. Bainbridge and J. A. Roper, J. gen. Microbiol.42, 417 (1966).PubMedGoogle Scholar
  2. 3.
    B. H. Nga and J. A. Roper, Genetics58, 193 (1968).PubMedGoogle Scholar
  3. 4.
    B. H. Nga and J. A. Roper, Genet. Res., Camb.14, 63 (1969).Google Scholar
  4. 5.
    J. A. Roper and B. H. Nga, Genet. Res., Camb.14, 127 (1969).Google Scholar
  5. 6.
    J. L. Azevedo and J. A. Roper, Genet. Res., Camb.16, 79 (1970).Google Scholar
  6. 7.
    G. Pontecorvo and E. Kafer, Adv. Genet.9, 71 (1958).PubMedGoogle Scholar
  7. 8.
    E. Kafer, Nature, Lond.186, 619 (1960).Google Scholar
  8. 9.
    E. Kafer, Genetics46, 1581 (1961).PubMedGoogle Scholar
  9. 10.
    P. Lhoas, Nature, Lond.190, 744 (1961).Google Scholar
  10. 11.
    A. C. Hastie, Nature, Lond.226, 771 (1970).Google Scholar
  11. 12.
    P. Cooke, J. A. Roper and W. A. Watmough, Nature, Lond.276, 276 (1970).Google Scholar
  12. 13.
    J. A. Roper, H. M. Palmer and W. A. Watmough, Mol. Gen. Genet.118, 125 (1972).PubMedGoogle Scholar
  13. 14.
    B. Shanfield and E. Kafer, Mutation Res.7, 487 (1969).PubMedGoogle Scholar
  14. 15.
    J. L. Azevedo, Genet. Res., Camb.26, 55 (1975).Google Scholar
  15. 16.
    K. W. Burr, H. M. Palmer and J. A. Roper, Heredity27, 487 (1971).Google Scholar
  16. 17.
    J. L. Azevedo, E. P. Santana and R. Bonatelli, Jr. Aspergillus Newsl.13, 5 (1975).Google Scholar
  17. 18.
    A. Levy and A. Ashri, Mutation Res.28, 397 (1975).Google Scholar
  18. 19.
    G. Pontecorvo, J. A. Roper, L. M. Hemmons, K. D. MacDonald and A. W. J. Bufton, Adv. Genet.5, 141 (1953).PubMedGoogle Scholar
  19. 20.
    K. S. McCully and E. Forbes, Genet. Res., Camb.6, 352 (1965).Google Scholar
  20. 21.
    J. A. Roper, Experientia8, 14 (1952).PubMedGoogle Scholar
  21. 22.
    C. H. Clarke and D. M. Shankel, Mutation Res.26, 473 (1974).PubMedGoogle Scholar
  22. 23.
    B. L. Case and J. A. Roper, Aspergillus Newsl.13, 8 (1975).Google Scholar
  23. 24.
    C. Ball and J. L. Azevedo, in: Second International Symposium on the Genetics of Industrial Microorganisms, p. 243. Ed. K. D. MacDonald. Academic Press, New York 1976.Google Scholar

Copyright information

© Birkhäuser Verlag 1977

Authors and Affiliations

  • R. BonatelliJr
    • 1
  • J. L. Azevedo
    • 1
  1. 1.Department of Genetics and Evolution, Institute of BiologyUniversity of CampinasSão Paulo(Brasil)

Personalised recommendations