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Serum and liver radioactivity levels in mice after intraperitoneal and subcutaneous injection of [14C]orotic acid

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Summary

[14C]Orotic acid was rapidly distributed in blood after, both i.p. and s.c. injection but was not completely absorbed from the peritoneal cavity until 20 min after injection. S.c. injection should be an acceptable alternative to i.p. injection although the incorporation into the liver acid soluble- and RNA-fractions was somewhat delayed after the s.c. injection.

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Authors and Affiliations

  1. Institute of Zoophysiology, University of Lund, Helgonavägen 3B, S-223 62, Lund, Sweden

    C. Engelbrecht, L. Lewan & T. Yngner

Authors
  1. C. Engelbrecht
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  2. L. Lewan
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  3. T. Yngner
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Additional information

This work was supported by grants from the Carl Trygger Foundation and the Foundation of Director Albert Påhlsson.

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Engelbrecht, C., Lewan, L. & Yngner, T. Serum and liver radioactivity levels in mice after intraperitoneal and subcutaneous injection of [14C]orotic acid. Experientia 33, 302–304 (1977). https://doi.org/10.1007/BF02002792

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  • DOI: https://doi.org/10.1007/BF02002792

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