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The effect of bovine myelin basic protein on uptake and release of H3-labelled 5-hydroxytryptamine, L-noradrenalin and γ-aminobutyric acid in rat cortex slices

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Summary

At concentrations above 10−5 M myelin basic protein (MBP) induced a small inhibition of the uptake of H3-5HT and H3-NA into rat cortex slices. Release of 5HT, NA and Gaba was not affected by 10−5 M MBP.

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Authors and Affiliations

  1. Abteilung Neurochemie, Neurologische Universitätsklinik, Socinstrasse 55, CH-4051, Basel, Switzerland

    C. G. Honegger, L. M. Krepelka, M. Steiner & H. P. von Hahn

Authors
  1. C. G. Honegger
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  2. L. M. Krepelka
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  3. M. Steiner
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  4. H. P. von Hahn
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Additional information

Acknowledgment. The authors wish to thank W. Bucher for the preparation of MBP.

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Honegger, C.G., Krepelka, L.M., Steiner, M. et al. The effect of bovine myelin basic protein on uptake and release of H3-labelled 5-hydroxytryptamine, L-noradrenalin and γ-aminobutyric acid in rat cortex slices. Experientia 33, 294–296 (1977). https://doi.org/10.1007/BF02002787

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  • DOI: https://doi.org/10.1007/BF02002787

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