, Volume 41, Issue 2, pp 275–276 | Cite as

The effect of castration, testosterone and estradiol on14C-serotonin metabolism by organ cultures of male rat pineal glands

  • S. Daya
  • B. Potgieter


The pineal gland of the male rat does not appear to rely on prior conversion of testosterone to estradiol for the stimulant effect of testosterone on pineal melatonin and 5-methoxytryptophol synthesis.

Key words

Rat pineal gland pineal gland rat estradiol testosterone methoxyindoles hydroxyindole-O-methyltransferase castration serotonin metabolism 


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Copyright information

© Birkhäuser Verlag 1985

Authors and Affiliations

  • S. Daya
    • 1
  • B. Potgieter
    • 2
  1. 1.Department of Pharmacology and TherapeuticsMedical University of Southern AfricaMedunsa(Republic of South Africa)
  2. 2.School of Pharmaceutical SciencesRhodes UniversityGrahamstown(Republic of South Africa)

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