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Long-term lowering of blood pressure after carotid and vertebrobasilar ischemic stroke

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Abstract

We followed up 107 patients experiencing a first-ever ischemic stroke after having been affected by essential hypertension for at least one year, in order to analyze the phenomenon of post-stroke blood pressure lowering. Of the 82 patients still surviving after three months of follow-up, 44 (54%) had normal arterial blood pressure values. There were no significant differences between these normotensive patients and the 38 with high blood pressure in terms of cerebrovascular risk factors or disability, but blood pressure normalized in 34 of the 54 patients experiencing a carotid stroke (63%) and in only 10 of the 28 experiencing vertebrobasilar stroke (36%) (p=0.035). These data may offer a starting point for further studies of the neurogenesis of arterial hypertension.

Sommario

Al fine di analizzare il fenomeno della normalizzazione della pressione arteriosa dopo ictus cerebrale in pazienti prima ipertesi, abbiamo osservato 107 soggetti con primo ictus ischemico, che erano già precedentemente affetti da ipertensione arteriosa da almeno un anno. Degli 82 (77%) sopravvissuti a tre mesi di follow-up, 44 (54%) hanno mostrato una normalizzazione della pressione arteriosa. L'incidenza di fattori di rischio per malattia cerebrovascolare e disabilità grave non è risultata significativamente diversa nel gruppo degli ipertesi rispetto ai normotesi. Tuttavia la normalizzazione della pressione arteriosa è stata osservata in 34 dei 54 pazienti con ictus carotideo (63%) e solo in 10 dei 28 con ictus vertebrobasilare (36%) (p=0.035). Riteniamo che tali dati offrano uno spunto per ulteriori ricerche sulla genesi neurogena dell'ipertensione arteriosa essenziale.

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  1. Divisione di Neurologia, Ospedale “Valduce”, Via Dante, 11, 22100, Como, Italy

    Guidotti M., Ciccone A., Garavaglia P. & Pellegrini G.

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  1. Guidotti M.
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  2. Ciccone A.
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  3. Garavaglia P.
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  4. Pellegrini G.
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Guidotti, M., Ciccone, A., Garavaglia, P. et al. Long-term lowering of blood pressure after carotid and vertebrobasilar ischemic stroke. Ital J Neuro Sci 17, 153–155 (1996). https://doi.org/10.1007/BF02000847

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