Skip to main content
SpringerLink
Log in

Glucose consumption by early and late-passage diploid human fibroblasts during growth and stationary phase

  • Specialia
  • Published:
Experientia Aims and scope Submit manuscript

Résumé

Les fibroblastes humains utilisent une quantité de glucose plus grande pendant leur croissance logarithmique que dans leur phase stationnaire. Les cultures à passage tardif consomment plus de glucose par cellule que les cultures à passage hâtif sans égard à la phase. Ce système doit être utile pour rechercher les altérations métaboliques au cours du vieillissement cellulaire et pour découvrir la base biochimique de certaines maladies dépendant de l'âge.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. A. Milunsky andJ. W. Littlefield, A. Rev. Med.23, 57 (1972).

    Article  CAS  Google Scholar 

  2. K. O. Raivio andJ. E. Seegmiller, A. Rev. Biochem.41, 543 (1972).

    Article  CAS  Google Scholar 

  3. L. Hayflick, Expl Cell Res.37, 614 (1965).

    Article  CAS  Google Scholar 

  4. S. Goldstein, J. W. Littlefield andJ. S. Soeldner, Proc. natn. Acad. Sci. USA64, 155 (1969).

    Article  CAS  Google Scholar 

  5. G. M. Martin, C. A. Sprague andC. J. Epstein, Lab. Invest.23, 86 (1970).

    CAS  PubMed  Google Scholar 

  6. S. Goldstein, New Engl. J. Med.285, 1120 (1971).

    Article  CAS  PubMed  Google Scholar 

  7. V. J. Cristofalo, Adv. Geront. Res.4, 45 (1972).

    CAS  Google Scholar 

  8. V. J. Cristofalo andD. Kritchevsky, Proc. Soc. exp. Biol. Med.118, 1109 (1965).

    Article  CAS  PubMed  Google Scholar 

  9. B. S. Danes, M. M. Broadfoot andJ. Paul, Expl. Cell Res.30, 369 (1963).

    Article  CAS  Google Scholar 

  10. V. J. Cristofalo andD. Kritchevsky, J. Cell Physiol.67, 125 (1966).

    Article  CAS  PubMed  Google Scholar 

  11. S. Goldstein andJ. W. Littlefield, Diabetes18, 545 (1969).

    Article  CAS  PubMed  Google Scholar 

  12. M. A. A. Condon, F. A. Oski, S. Dimauro andW. J. Mellman, Nature New Biol.229, 214 (1971).

    Article  CAS  PubMed  Google Scholar 

  13. R. Andres, T. Pozefsky andR. S. Swerdloff, inAdvances in Metabolic Disorders, Suppl. 1 (Eds.R. A. Camerini-Davalos andH. S. Cole; Academic Press, Inc., New York 1970), p. 349.

    Google Scholar 

  14. S. Goldstein, E. J. Moerman andJ. S. Soeldner, J. clin. Invest.53, 27a (1974).

    Google Scholar 

  15. J. T. Cooper andS. Goldstein, Atherosclerosis20, 41 (1974).

    Article  CAS  PubMed  Google Scholar 

  16. S. Goldstein, Humangenetik12, 83 (1971).

    CAS  PubMed  Google Scholar 

  17. M. W. Slein, inMethods of Enzymatic Analysis (Ed.H. U. Bergmeyer; Academic Press, Inc., New York 1965), p. 117.

    Chapter  Google Scholar 

  18. P. F. Kruse Jr. andE. Miedema, Proc. Soc. exp. Biol. Med.119, 1110 (1965).

    Article  CAS  PubMed  Google Scholar 

  19. V. J. Cristofalo, B. V. Howard andD. Kritchevsky, inOrganic Biological and Medicinal Chemistry (Eds.U. Gallo andL. Santamaria; Noord Hollandsche Uitgevers-MIJ, Amsterdam 1970), p. 95.

    Google Scholar 

  20. R. J. Haslam andS. Goldstein, Biochem. J.144, 253 (1974).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. C. W. Castor, R. K. Prince andE. L. Dorstewitz, Lab. Invest.11, 703 (1962).

    CAS  PubMed  Google Scholar 

  22. M. W. Steele andK. E. Owens, Biochem. Genet.9, 147 (1972).

    Article  Google Scholar 

Download references

Author information

Author notes

  1. G. Trieman

    Present address: School of Dentistry, University of Western Ontario, London, Ontario, Canada

Authors and Affiliations

  1. Department of Medicine and Biochemistry, McMaster University Medical Centre, L8S 4J9, Hamilton, Ontario, Canada

    S. Goldstein & G. Trieman

Authors
  1. S. Goldstein
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. Trieman
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

We thank Mrs,Elena Moerman for expert technical assistance. Supported by grants from the Medical Research Council of Canada and the Canadian Diabetic Association Foundation Fund during the tenure of a scholarship from the M.R.C. (SG).

Rights and permissions

Reprints and permissions

About this article

Cite this article

Goldstein, S., Trieman, G. Glucose consumption by early and late-passage diploid human fibroblasts during growth and stationary phase. Experientia 31, 177–180 (1975). https://doi.org/10.1007/BF01990690

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01990690

Keywords

Search

Navigation