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Further studies on the effect of imipramine and desipramine on uridine diphosphate glucuronyl transferase

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Nous avons recherché l'action de l'imipramine et de la désipramine sur l'UDP glucuronyle transférase dans les microsomes hépatiques. Les concentrations de ces drogues entre 1 et 5 mM ont activé l'enzyme. Ce sont des surfactants cationiques.

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Authors and Affiliations

  1. Area Department of Pathology, Church Lame, Heavitree, Exeter, Devonshive, England

    R. F. Piper & T. Hargreaves

Authors
  1. R. F. Piper
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  2. T. Hargreaves
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Additional information

We thank the South Western Regional Hospital Board and the Northcott Devon Medical Foundation for generous financial assistance and Geigy Pharmaceutical Co. Ltd., for gifts of imipramine and desipramine.

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Piper, R.F., Hargreaves, T. Further studies on the effect of imipramine and desipramine on uridine diphosphate glucuronyl transferase. Experientia 31, 159–160 (1975). https://doi.org/10.1007/BF01990679

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