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Inhibitors of prostaglandin catabolism. I. Differential sensitivity of 9-PGDH, 13-PGR and 15-PGDH to low concentrations of indomethacin

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Zusammenfassung

Es zeigt sich, dass jedes der 3 Enzyme, die den Abbau von Prostaglandin in den Nieren erwachsener Ratten verursachen, durch schwache Konzentrationen von Indomethacin in steigendem Ausmass inhibiert werden könne: 9-PGDH>13-PGR>15-PGDH.

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Authors and Affiliations

  1. Research Institute, The Hospital for Sick Children, 555 University Avenue, M5G 1X8, Toronto, Canada

    C. Pace-Asciak & S. Cole

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  1. C. Pace-Asciak
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  2. S. Cole
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Pace-Asciak, C., Cole, S. Inhibitors of prostaglandin catabolism. I. Differential sensitivity of 9-PGDH, 13-PGR and 15-PGDH to low concentrations of indomethacin. Experientia 31, 143–145 (1975). https://doi.org/10.1007/BF01990669

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