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Hyperglycemic effect in the rabbit induced by ACTH4–10

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Summary

In the rabbit, a single i.v. administration of ACTH4–10 (130 μg/kg) induces hyperglycemia. As ACTH4–10 also induces hypocalcemia and inhibits insulin secretion, we suggest that hypocalcemia, inhibition of insulin secretion, and hyperglycemia, are closely related.

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Authors and Affiliations

  1. Laboratoire de Neurophysiologie, Université de Bordeaux II, INSERM U.53, Domaine de Carreire, Rue Camille Saint-Saëns, F-33077, Bordeaux cedex, France

    R. Drouhault, A. M. Courtes & B. Dufy

Authors
  1. R. Drouhault
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  2. A. M. Courtes
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  3. B. Dufy
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Additional information

We are grateful to Professor A. Baghdiantz for his helpful advice, critical reading of the manuscript and numerous helpful discussions during this study, and to Miss A. Ferret-Bouin for her technical assistance.

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Drouhault, R., Courtes, A.M. & Dufy, B. Hyperglycemic effect in the rabbit induced by ACTH4–10. Experientia 39, 920–922 (1983). https://doi.org/10.1007/BF01990439

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  • DOI: https://doi.org/10.1007/BF01990439

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