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Experientia

, Volume 39, Issue 8, pp 891–892 | Cite as

Low doses of 2,4,5-trichlorophenoxyacetic acid are behaviorally teratogenic to rats

  • M. A. Crampton
  • L. J. Rogers
Short Communications Pharmacology, Tocicology

Summary

Pre-natal exposure of rats to 2,4,5-T has long-term effects on behavior. A test for novelty responding detects abnormalities after exposure to a single dose as low as 6 mg/kg on day 8 of gestation. This is well below doses reported to be morphologically teratogenic, and raises concern for human exposure.

Keywords

Single Dose Human Exposure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Birkhäuser Verlag 1983

Authors and Affiliations

  • M. A. Crampton
    • 1
  • L. J. Rogers
    • 1
  1. 1.Department of PharmacologyMonash UniversityClayton(Australia)

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