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Mg2+-HCO −3 -ATPase and carbonic anhydrase in rat intestinal mucosa

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Summary

Mg2+-dependent and HCO −3 -stimulated ATPase activity was highest in the brush border (microvilli) of rat duodenal mucosa compared with that of the other gastrointestinal mucosa. This ATPase may be useful to neutralize the gastric acid in the duodenal lumen. Carbonic anhydrase seems to accomplish a subsidiary role in the above reaction.

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Authors and Affiliations

  1. Department of Pharmacology, Kanazawa Medical University, Uchinada, 920-02, Ishikawa, Japan

    S. Suzuki & N. Ozaki

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  1. S. Suzuki
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  2. N. Ozaki
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Suzuki, S., Ozaki, N. Mg2+-HCO −3 -ATPase and carbonic anhydrase in rat intestinal mucosa. Experientia 39, 872–873 (1983). https://doi.org/10.1007/BF01990412

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  • DOI: https://doi.org/10.1007/BF01990412

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