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Estimation of the odorous steroid, 5α-androst-16-en-3-one, in human saliv

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Summary

The concentration of the urine-smelling steroid, 5α-androst-16-en-3-one, has been measured by radioimmunoassay in the saliva of 9 men and 4 women. The lower limit of detection was estimated to be 0.725 nmoles/1. In six of the men the range of concentrations of the odorous steroid was 0.8–1.8 nmoles/1 saliva (3 men had less than the estimated lower limit of detection). In only one of the women studied could the 5α-androst-16-en-3-one be measured (0.83 nmoles/l) in the saliva.

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References

  1. Gower, D.B., J. Steroid Biochem.3 (1972) 45.

    Article  CAS  PubMed  Google Scholar 

  2. Reed, H.C.B., Melrose, D.R., and Patterson, R.L.S., Br. vet. J.130 (1974) 61.

    Article  CAS  PubMed  Google Scholar 

  3. Brooksbank, B.W.L., and Haslewood, G.A.D., Biochem. J.80 (1961) 488.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Claus, R., and Alsing, W., J. Endocr.68 (1976) 483.

    Article  CAS  PubMed  Google Scholar 

  5. Bird, S., and Gower, D.B., J. Steroid Biochem.14 (1981) 213

    Article  CAS  PubMed  Google Scholar 

  6. Labows, J.N., Preti, G., Hoelzle, E., Leyden, J., and Kligman, A., Steroids34 (1979) 249.

    Article  CAS  PubMed  Google Scholar 

  7. Bird, S., and Gower, D.B, J. Steroid Biochem.17 (1982) 517.

    Article  CAS  PubMed  Google Scholar 

  8. Leyden, J.J., McGinley, K.J., Hoelzle, E., Labows, J.N., and Kligman, A., J. Invest. Dermat.77 (1981) 413.

    Article  CAS  Google Scholar 

  9. Cowley, J.J., Johnson, A.L., and Brooksbank, B.W.L., Psychoneuroendocrinology2 (1977) 159.

    Article  CAS  PubMed  Google Scholar 

  10. Kirk-Smith, M., Booth, D. A., Carrol, D., and Davies, P., Res. Commun. Psychol. Psychiat. Behav.3 (1978), 379.

    CAS  Google Scholar 

  11. Kirk-Smith, M., and Booth, D. A. in: Olfaction and taste VII, p. 397. Ed. H. van der Starre. Information Retrieval Ltd, Oxford 1980.

    Google Scholar 

  12. Amoore, J. E., Pelosi, P., and Forrester L. J., Chem. Senses Flav.2 (1977) 401.

    Article  CAS  Google Scholar 

  13. Doty, R. L., Orndorff, M. M., Leyden, J., and Kligman, A., Behav. Biol.23 (1978) 373.

    Article  CAS  PubMed  Google Scholar 

  14. Walker, R. F., Riad-Fahmy, D., and Read, G. F., Clin. Chem.24 (1978) 1460.

    Article  CAS  PubMed  Google Scholar 

  15. Riad-Fahmy, D., Read, G. F., and Walker, R. F., J. clin. Chem. Biochem.19, (1981) 602.

    Google Scholar 

  16. Landman, A. D., Sanford, L. M., Howland, B. E., Dawes, C., and Pritchard, E. T., Experientia32 (1976) 940.

    Article  CAS  PubMed  Google Scholar 

  17. Andresen, Ø., Acta endocr., Copenh.76 (1974) 377.

    CAS  Google Scholar 

  18. Brooksbank, B. W. L., Wilson, D. A. A., and Gustafsson, J.-Å., Steroids Lipids Res.3 (1972) 263.

    CAS  PubMed  Google Scholar 

Download references

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Author notes

  1. S. Bird

    Present address: Department of Chemical Pathology, StGeorge's Hospital Medical School, SW17, London, England

Authors and Affiliations

  1. Department of Biochemistry, Guy's Hospital Medical School, SE19RT, London, England

    S. Bird & D. B. Gower

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  1. S. Bird
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  2. D. B. Gower
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Supported by the Herbert Dunhill Trust.

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Bird, S., Gower, D.B. Estimation of the odorous steroid, 5α-androst-16-en-3-one, in human saliv. Experientia 39, 790–792 (1983). https://doi.org/10.1007/BF01990330

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