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Effects of prednisolone and butyrate on agglutinability of HeLa cells by concanavalin A

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Summary

Agglutinability by concanavalin A was measured with HeLa65 cells grown with prednisolone or sodium butyrate, 2 compounds that increase the activity of the carcinoplacental form of alkaline phosphatase, an enzyme localized in membranes. Prednisolone enhanced concanavalin A agglutination approximately 3-fold while sodium butyrate had no effect.

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Authors and Affiliations

  1. Departments of Pharmacology and Medicine, New York University School of Medicine, 10016, New York, New York, USA

    S. G. Sullivan, N. K. Ghosh, S. I. Deutsch, D. G. Day & R. P. Cox

  2. Department of Psychiatry, Bronx Veterans Administration Medical Center, 10468, Bronx, New York, USA

    S. G. Sullivan, N. K. Ghosh, S. I. Deutsch, D. G. Day & R. P. Cox

  3. Department of Medicine, Case Western Reserve University School of Medicine and Cleveland Veterans Administration Medical Center, 44106, Cleveland, Ohio, USA

    S. G. Sullivan, N. K. Ghosh, S. I. Deutsch, D. G. Day & R. P. Cox

Authors
  1. S. G. Sullivan
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  2. N. K. Ghosh
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  3. S. I. Deutsch
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  4. D. G. Day
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  5. R. P. Cox
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Additional information

Acknowledgments. This research was supported by grants from the American Cancer Society and the Veterans Administration.

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Sullivan, S.G., Ghosh, N.K., Deutsch, S.I. et al. Effects of prednisolone and butyrate on agglutinability of HeLa cells by concanavalin A. Experientia 39, 788–790 (1983). https://doi.org/10.1007/BF01990329

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  • DOI: https://doi.org/10.1007/BF01990329

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