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Serum inhibitory activity on granulocyte-macrophage colony formation

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Summary

Normal and chloroform-extracted human sera, fractionated by Sephadex column chromatography, have been tested for inhibitory activity on granulocyte-macrophage (GM) colony formation. It was found that this activity is connected with lipoproteins (inhibitors of granulocyte-macrophage colony stimulating factor) and low molecular weight substances (7000; 13,000) which can act as specific polypeptide chalones.

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Authors and Affiliations

  1. Department of Clinical Diagnostics, Institute of Biochemistry and Medical Analytics, Medical School, PL-15-276, Biaŀystok, Poland

    M. Szmitkowski

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  1. M. Szmitkowski
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Szmitkowski, M. Serum inhibitory activity on granulocyte-macrophage colony formation. Experientia 39, 771–772 (1983). https://doi.org/10.1007/BF01990319

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  • DOI: https://doi.org/10.1007/BF01990319

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