Summary
Considerable amounts of nonesterified cholesterol were found in human serum freed from lipoproteins. This cholesterol, when incubated with synaptosomal plasma membranes of dog brain, evokes changes of the ouabain-sensitive ATPase activity, as the exogenously added cholesterol does.
References
Alivisatos, S.G.A., Deliconstantinos, G., Papaphilis, A., and Theodosiadis, G., Biochim. biophys. Acta643 (1981) 642.
Alivisatos, S.G.A., Deliconstantinos, G., and Theodosiadis, G., Biochim. biophys. Acta643 (1981) 650.
Papaphilis, A., and Deliconstantinos, G., Biochem. Pharmac.29 (1980) 3325.
Alivisatos, S.G.A., and Deliconstantinos, G.: On cell function and differentiation, p. 479–489. Ed. A. Evangellopoulos. Alan R. Liss Inc., New York 1982.
Deliconstantinos, G., Anastasopoulou, K., and Karayannakos, P., Biochem. Pharmac.32 (1983) 1309.
Havel, R.J., Eder, H.A., and Bradgon, J.H., J. clin. Invest.34 (1955) 1345.
Noble, R.P., J. Lipid Res.9 (1968) 693.
Zak, B., Am. J. clin. Path.27 (1957) 583.
Folch, J., Lees, M., and Sloane-Stanley, G.M., J. biol. Chem.226 (1957) 497.
Brown, M.S., Faust, J.R., and Goldstein, J.L., J. clin. Invest.55 (1975) 783.
Lowry, O.M., Rosenbrough, N.J., Farr, N.L., and Randal, R.J., J. biol. Chem.193 (1951) 265.
Phillips, M.C., Mclean, L.R., Stoudt, G.W., and Rothblat, G.H., Atherosclerosis36 (1980) 409.
Gottlieb, M.H., Biochim. biophys. Acta600 (1980) 530.
Deliconstantinos, G., Experientia37 (1981) 81.
Klein, K., Moore, L., and Pastan, I., Biochim. biophys. Acta506 (1978) 42.
Portman, O.W., Adv. Lipid Res.8 (1970) 41.
Author information
Authors and Affiliations
Additional information
Acknowledgments. I am most grateful to Professor S.G.A. Alivisatos for useful suggestions during the preparation of this manuscript. Appreciation is expressed to Miss K. Anastasopoulou for the electrophoretic runs of lipoproteins.
Rights and permissions
About this article
Cite this article
Deliconstantinos, G. Free cholesterol not carried by lipoproteins in human serum. Experientia 39, 748–750 (1983). https://doi.org/10.1007/BF01990306
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01990306