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Dermatomic distributions of hypopigmented macular lesions of leprosy: neural dependence of melanocytic functions

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  • Physiology, Pathophysiology
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Summary

Dermatomic analysis of the distribution of the hypopigmented patches of leprosy has revealed a pattern wherein patches are most frequent in dermatomes of the brachial plexus, decrease gradually in frequency in succeeding spinal segments and increase again in dermatomes of the lumbar plexus. The predilection of hypopigmented patches for certain dermatomes may be a reflection of easy vulnerability of the neural pigmentary mechanism and/or a reflection of selective multiplication ofM. leprae in nerves of certain dermatomes, even though the organisms might have been seeded all over the body by hematogenous spread. These preliminary observations are discussed.

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References

  1. Jacobowitz, D. M., and Laties, A. M., Anat. Rec.162 (1968) 501.

    Article  CAS  PubMed  Google Scholar 

  2. Wimster, I. W., Br. J. Derm.77 (1965) 397.

    Google Scholar 

  3. Gauthier, Y., Surleve Bazeille, J. E., Gauthier, O., and Taxier, M. L., Bull. Soc. fr. Derm. Syph.81 (1974) 81.

    Google Scholar 

  4. Chanco-Turner, M. L., and Lerner, A. B., Archs Derm.91 (1965) 390.

    Article  CAS  Google Scholar 

  5. Lerner, A. B., and Nordlund, J. J., J. Am. med. Ass.239 (1978) 1183.

    Article  CAS  Google Scholar 

  6. Lerner, A. B., Snell, R. S., Chanco-Turner, M. L., and McGuire, J. S., Archs Derm.94 (1966) 269.

    Article  CAS  Google Scholar 

  7. Cochrane, R. G., in: Leprosy in theory and practice, p. 251. Eds R. G. Cochrane and T. F. Davey. John Wright, Bristol 1964.

    Google Scholar 

  8. Lerner, A. B., J. invest. Derm.32 (1959) 285.

    Article  CAS  PubMed  Google Scholar 

  9. Scholtz, J. R., and Willanson, Jr, C., Archs Derm. Syph.64 (1951) 366.

    Article  CAS  Google Scholar 

  10. Ridley, D. S., and Jopling, W. H., Lepr. Rev.33 (1962) 119.

    CAS  PubMed  Google Scholar 

  11. Badger, L. F., in: Leprosy in theory and practice, p. 69. Eds R. G. Cochrane and T. F. Davey. John Wright, Bristol 1964.

    Google Scholar 

  12. Cochrane, R. G., A practical textbook of leprosy, p. 1. Oxford University Press, London 1947.

    Google Scholar 

  13. Selvapandian, A. J., Muliyil, J., Joseph, A., Kuppusamy, P., and Martin, G. G., Lepr. India52 (1980) 209.

    Google Scholar 

  14. Jopling, W. H., in: Handbook of Leprosy, p. 1. Ed. W. H. Jopling. William Heinemann Medical Books, London 1978.

    Google Scholar 

  15. Ivanova, N. A., Bull. WHO46 (1972) 515.

    CAS  PubMed  PubMed Central  Google Scholar 

  16. Karat, A. B. A., Job, C. K., and Rao, P. S. S., Br. med. J.1 (1971) 307.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Singh, R., and Koranne, R. V., Lepr. India51 (1979) 451.

    CAS  PubMed  Google Scholar 

  18. Weddell, G., and Palmer, E., Lepr. Rev.34 (1963) 57.

    CAS  PubMed  Google Scholar 

  19. Singh, K., Iyenger, B., and Singh, R., Lepr. India, accepted.

  20. Abramowitz, A. A., Biol. Bull. mar. biol. Lab., Woods Hole71 (1936) 259.

    Article  Google Scholar 

  21. Brucke, E., Denkschr. Akad. Wiss., Wien4 (1852) 179.

    Google Scholar 

  22. Frisch, K. von, Pflügers Arch. ges. Physiol.138 (1911) 319.

    Article  Google Scholar 

  23. Gray, E. G., J. Exp. Biol.33 (1956) 448.

    Article  Google Scholar 

  24. Pouchet, G., J. Anat. Physiol., Paris12 (1876) 1.

    Google Scholar 

  25. Ehinger, B., Z. Zellforsch. mikrosk. Anat.116 (1971) 157.

    Article  CAS  PubMed  Google Scholar 

  26. Ehinger, B., and Falack, B., Z. Zellforsch. mikrosk. Anat.105 (1970) 538.

    Article  CAS  PubMed  Google Scholar 

  27. Laties, A. M., Invest. Ophthal.11 (1972) 555.

    CAS  PubMed  Google Scholar 

  28. Uga, S., Ishikawa, S., and Mukuno, K., Invest. Ophthal. vis. Sci.16 (1977) 877.

    CAS  PubMed  Google Scholar 

  29. Mukuno, K., and Witmer, R., Albrecht v. Graefes Arch. Ophthal.203 (1977) 1.

    Article  CAS  Google Scholar 

  30. Cauna, N., J. Anat.115 (1973) 277.

    CAS  PubMed  PubMed Central  Google Scholar 

  31. Orfanos, C. E., and Mahrle, G., J. invest. Derm.61 (1973) 108.

    Article  CAS  PubMed  Google Scholar 

  32. Tsuji, T., J. invest. Derm.57 (1971) 247.

    Article  CAS  PubMed  Google Scholar 

  33. Breathnach, A. S., Bor, S., and Wyllie, A. A., J. invest. Derm.47 (1966) 125.

    Article  CAS  PubMed  Google Scholar 

  34. Mishima, Y., Br. J. Derm.79 (1967) 611.

    Article  CAS  Google Scholar 

  35. Mishima, Y., and Milinska, A. M., J. invest. Derm.37 (1961) 107.

    Article  CAS  PubMed  Google Scholar 

  36. Waring, H., Biol. Rev.17 (1942) 120.

    Article  CAS  Google Scholar 

  37. Gladstone, R. M., Archs Neurol.21 (1969) 184.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Dermatology and Venereology, and Department of Pathology, Maulana Azad Medical College and Associated J.P. & G. B. Pant Hospitals, 110002, New Delhi, India

    K. Singh, B. Iyenger & R. Singh

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  1. K. Singh
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  2. B. Iyenger
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  3. R. Singh
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Singh, K., Iyenger, B. & Singh, R. Dermatomic distributions of hypopigmented macular lesions of leprosy: neural dependence of melanocytic functions. Experientia 39, 723–725 (1983). https://doi.org/10.1007/BF01990292

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