Summary
Alpha-tocopherol inhibits human platelet aggregation induced by arachidonate sodium, collagen, epinephrine, adenosine diphosphate or thrombin — arachidonate sodium being the most susceptible. The second phase of the biphasic platelet aggregation induced by epinephrine or adenosine diphosphate is preferentially inhibited.
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This work was supported by the Medical Research Council of Canada, Quebec Medical Council, and a Fraser Scholarship, McGill University. I thank Drs.K. N. Drummond andS. O'Regan for their comments.
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Fong, J.S.C. Alpha-tocopherol: Its inhibition on human platelet aggregation. Experientia 32, 639–641 (1976). https://doi.org/10.1007/BF01990209
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DOI: https://doi.org/10.1007/BF01990209