Summary
Action of 100 mg/kg of 5,7-dihydroxytryptamine on Auerbach's plexus in the ileum of the guinea-pig has been studied using Falck and Hillarp's formaldehyde condensation technique. The drug caused partial disappearance of the adrenergic nerve profiles initially but after 10 days of treatment all the lost fibers reappeared.
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The author is thankful to Professor G. Burnstock, Department of Anatomy and Embryology, University College London, London, England (where part of the work was done) for providing facilities.
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Qayyum, M.A. Effect of 5,7-dihydroxytryptamine on auerbach's plexus in the ileum of guinea-pig. Experientia 39, 1385–1386 (1983). https://doi.org/10.1007/BF01990116
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DOI: https://doi.org/10.1007/BF01990116