, Volume 39, Issue 12, pp 1355–1356 | Cite as

Cyclic AMP accumulation in human fibroblast cultures: diabetics compared with normals

  • B. Israelsson
  • J. Malmquist
  • T. Kjellström
Short Communications Physiology, Pathophysiology


Isoproterenol-stimulated accumulation of adenosine 3′,5′-monophosphate (cyclic AMP) in skin fibroblast cultures from type 2 diabetics was twice as high as in fibroblasts from control subjects.


Adenosine Control Subject Monophosphate Human Fibroblast Skin Fibroblast 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Goldstein, S., J. Invest. Dermat.73 (1979) 19.Google Scholar
  2. 2.
    Goldstein, S., Moerman, E.J., Soeldner, J.S., Gleason, R.E., and Barnett, D.M., Science199 (1978) 781.Google Scholar
  3. 3.
    Vracko, R., and Benditt, E.P., Fedn Proc.34 (1975) 68.Google Scholar
  4. 4.
    Vracko, R., and McFarland, B.H., Exp. Cell Res.129 (1980) 345.Google Scholar
  5. 5.
    Friedman, D.L., Physiol. Rev.56 (1976) 652.Google Scholar
  6. 6.
    Butcher, R.W., J. cyclic Nucleotide Res.4 (1978) 411.Google Scholar
  7. 7.
    Belfield, A., and Goldberg, D.M., Clin. Chem.15 (1969) 931.Google Scholar
  8. 8.
    Barber, R., Kelly, L.A., McGuire, R.F., and Butcher, R.W., J. cyclic Nucleotide Res.3 (1977) 249.Google Scholar
  9. 9.
    Salomon, Y., Londos, C., and Rodbell, M., Analyt. Biochem.58 (1974) 541.Google Scholar
  10. 10.
    Böhlen, P., Stein, S., Dairman, W., and Udenfriend, S., Archs Biochem. Biophys.155 (1973) 213.Google Scholar
  11. 11.
    Kelly, L.A., Wu, C., and Butcher, R.W., J. cyclic Nucleotide Res.4 (1978) 423.Google Scholar
  12. 12.
    Rowe, D.W., Starman, B.J., Fujimoto, W.F., and Williams, R.H., Diabetes26 (1977) 284.Google Scholar

Copyright information

© Birkhäuser Verlag 1983

Authors and Affiliations

  • B. Israelsson
    • 1
  • J. Malmquist
    • 1
  • T. Kjellström
    • 1
  1. 1.Department of MedicineUniversity of Lund, Malmö General HospitalMalmö(Sweden)

Personalised recommendations