Altered circadian rhythm of catecholamines in patients with apallic syndrome
- 16 Downloads
Circadian rhythms of catecholamines were investigated in 4 healthy subjects and in 6 patients suffering from an apallic syndrome. The clinical picture of this syndrome is characterized by disturbed consciousness (coma vigile), by suspension of the sleeping and waking rhythm, by lack of emotional reactions and by appearance of primitive motor patterns. 5 of the 6 apallic patients showed an abolished rhythmicity compared with the control group. These results were interpreted as an indication that endogenous, centrally controlled processes are the cause of circadian rhythms.
KeywordsHealthy Subject Catecholamine Control Process Circadian Rhythm Clinical Picture
Unable to display preview. Download preview PDF.
- 3.J. Aschoff, A. Rev. Physiol.25, 581 (1963).Google Scholar
- 4.F. Halberg and A. Ahlgren, Int. J. Chronobiol.6, 145 (1979).Google Scholar
- 5.J. Aschoff, M. Fatranska, H. Giedke, P. Doerr, D. Stamm and H. Wisser, Science171, 213 (1971).Google Scholar
- 6.F. Halberg, Z. Vitam-, Horm- u. Fermentforsch.10, 225 (1959).Google Scholar
- 7.G. Dalle Ore, F. Gerstenbrand, C.H. Lücking, G. Peters and U.H. Peters, The Apallic syndrome. Springer, Berlin-Heidelberg-New York 1977.Google Scholar
- 8.B. Rusak and I. Zucker, Physiol. Rev.59, 449 (1979).Google Scholar
- 9.J.D. Peuler and G.A. Johnson, Life Sci.21, 625 (1977).Google Scholar
- 10.E. Weber, in: Grundriss der biologischen Statistik, 7th edn, p. 534. Gustav Fischer, Stuttgart 1972.Google Scholar