, Volume 37, Issue 11, pp 1139–1141 | Cite as

Acidic glycosaminoglycans in human coronary arteries, with special reference to the presence of heparin or related glucosaminoglycan

  • K. Murata
  • Y. Yokoyama


Acidic glycosaminoglycans (AGAG) in 3 branches of the human coronary artery were enzymatically analyzed. The main AGAG were heparan sulfate, chondroitin sulfates and dermatan sulfate. The yield of AGAG decreased in the order of left, right and peripheral branches. Heparin or a related glucosaminoglycan were dominant in the peripheral branch.


Sulfate Coronary Artery Heparin Special Reference Heparan Sulfate 
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  1. 2.
    K. Izuka and K. Murata, Atherosclerosis16, 217 (1972).Google Scholar
  2. 3.
    K. Murata, K. Nakazawa and A. Hamai, Atherosclerosis21, 93 (1975).Google Scholar
  3. 4.
    K. Murata, K. Izuka and K. Nakazawa, Atherosclerosis29, 95 (1978).Google Scholar
  4. 5.
    E. Buddecke, Z. physiol. Chem.318, 33 (1960).Google Scholar
  5. 6.
    V. Kumar, G.S. Berenson, H. Ruiz, E.R. Dalferes, Jr, and J.P. Strong, J. Atheroscler. Res.7, 573 (1967).Google Scholar
  6. 7.
    R.L. Stevens, M. Colombo, J.J. Gonzales, W. Hollander and K. Schmid, J. clin. Invest.58, 470 (1976).Google Scholar
  7. 8.
    K. Izuka and K. Murata, Experientia29, 655 (1973).Google Scholar
  8. 9.
    K. Murata, Connect. Tissue Res.6, 131 (1978).Google Scholar
  9. 10.
    C. Velican and D. Velican, Atherosclerosis29, 141 (1978).Google Scholar
  10. 11.
    M. Tammi, P.O. Seppälä, A. Lehtonen and M. Möttönen, Atherosclerosis29, 191 (1978).Google Scholar
  11. 12.
    I.N. Likar, R.W. Robinson and L.J. Likar, Atherosclerosis38, 231 (1981).Google Scholar
  12. 13.
    K. Murata, in: Methods in Carbohydrate Chemistry, Vol. 8, p. 81. Ed. R.L. Whistler and J.N. BeMiller. Academic Press, New York 1980.Google Scholar
  13. 14.
    K. Murata, T. Ogura and T. Okuyama, Connect. Tissue Res.2, 101 (1974).Google Scholar
  14. 15.
    N. Seno, K. Anno, K. Kondo, S. Nagase and S. Sato, Analyt. Biochem.33, 197 (1970).Google Scholar
  15. 16.
    E. Wessler, Analyt. Biochem.26, 439 (1968).Google Scholar
  16. 17.
    T. Bitter and H. Muir, Analyt. Biochem.4, 330 (1962).Google Scholar
  17. 18.
    Z. Yoshizawa, Biochim. biophys. Acta141, 600 (1967). The heparinase (EC. was prepared fromFlavobacterium heparinum and purified through ion-exchange chromatography. The enzyme digests specifically heparin from HS.Google Scholar
  18. 19.
    E. Moczar, M. Moczar, G. Schillinger and L. Robert, J. Chromat.31, 561 (1967).Google Scholar
  19. 20.
    R. Hata and Y. Nagai, Analyt. Biochem.45, 462 (1972).Google Scholar
  20. 21.
    J.E. Jorpes, H.J. Holgren and O. Wilander, Z. mikrosk.-anat. Forsch.42, 279 (1937).Google Scholar
  21. 22.
    O.J. Pollak, Circulation12, 490 (1955).Google Scholar
  22. 23.
    K. Murata and K. Nakazawa, Atherosclerosis25, 31 (1976).Google Scholar

Copyright information

© Birkhäuser Verlag 1981

Authors and Affiliations

  • K. Murata
    • 1
  • Y. Yokoyama
    • 1
  1. 1.Department of Medicine and Physical TherapyUniversity of Tokyo School of MedicineTokyo(Japan)

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