Experientia

, Volume 37, Issue 8, pp 807–809 | Cite as

The serum levels of unbound bilirubin that induce changes in some brain mitochondrial reactions in newborn guinea-pigs

  • Maria A. S. Almeida
  • L. RezendeJr
Specialia

Summary

Bilirubin in different concentrations was injected in newborn guinea-pigs and the following parameters were determined: serum total and unbound bilirubin, whole brain bilirubin content and oxygen consumption, NADH-cytochrome c reductase and ATPase activities in brain mitochondria. The results showed a significant correlation between decreased rates of brain metabolism and the elevation of serum total and unbound bilirubin.

Keywords

Oxygen Serum Level Bilirubin Oxygen Consumption ATPase Activity 

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Copyright information

© Birkhäuser Verlag 1981

Authors and Affiliations

  • Maria A. S. Almeida
    • 1
  • L. RezendeJr
    • 1
  1. 1.Department of Biochemistry and Immunology of the Federal University of Minas GeraisBelo Horizonte(Brazil)

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