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Inheritance of harelip and cleft palate in man

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Summary

The observations ofBirkenfeld, Schröder and ofSanders on harelip and cleft palate in man can be arranged in such a way that they all support the hypothesis that the trait is inherited as a double recessive, one gene being autosomal and the other one sex-linked. This explains the fact that harelip is twice as common in the male sex as it is in the female.

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Literature Cited

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Fortuyn, A.B.D. Inheritance of harelip and cleft palate in man. Genetica 17, 349–366 (1935). https://doi.org/10.1007/BF01985019

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  • DOI: https://doi.org/10.1007/BF01985019

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